C H E M P L O Y M E N T  A B S T R A C T S  -   MAY 2007

 

 

CHEMPLOYMENT 609

 

Position Title

Research Scientist, Medicinal Chemistry,  San Diego, CA

 

Job Description

Medicinal chemistry. Carry out the design and synthesis of new chemical entities suitable for driving a drug discovery program from the drawing board to the clinic.

 

QUALIFICATIONS DESIRED

A Ph.D. (0-5 years) or M.S. (3-10 years) in synthetic organic chemistry with demonstrated success in modern approaches to multi-step organic synthesis is required. The successful candidates must thrive in a team oriented environment and be able to work efficiently in an early stage discovery company. Structure based drug design experience is a plus.

 

Description of Company

Trius Therapeutics is discovering and developing innovative antibacterial drugs for the treatment of life-threatening infections. The companyÕs lead product candidate, TR-701 is a novel oral and IV oxazolidinone antibiotic with potent activity against Gram positive bacterial pathogens. TriusÕ pipeline includes three additional structure-based drug design programs directed against novel antibacterial targets. For more information, visit www.triusrx.com. 

 

Application Instructions

Interested candidates please e-mail resumes to careers@triusrx.com.

 

                                           

CHEMPLOYMENT 610

 

Position Title

Senior Chemist

 

Job Description

Candidates will work within the oligonucleotide production team at the US facility of Eurogentec, an International biotechnology company.

 

QUALIFICATIONS DESIRED

Candidates must have a chemistry background, excellent communication skills and the ability to work well within a team environment. The ability to work to ISO9000 accreditation standards is essential. Experience with oligonucleotide synthesis, purification and QC is desirable but full training will be provided.

 

Description of Company

Eurogentec is a global supplier of molecular biology reagents.

www.eurogentec.com

 

Application Instructions

For more information or to apply for this post, please contact Dr Catherine McKeen at c.mckeen@eurogentec.com.

 

 

CHEMPLOYMENT 611

 

Position Title

Sr. Scientist - Medicinal Chemistry

 

Job Description

-  Design, develop synthetic routes, and  synthesize compounds directed towards  drug candidates.

-  Design synthetic targets and viable synthetic  routes, and synthesize target molecules

-  Develop structure-activity relationships  using biological as well as DMPK data

-  Conduct and interpret spectral and other  analytical data independently

- Present data and compose scientific papers  for publication

- Demonstrate creativity, inventiveness and innovation to advance drug discovery independently 

 

QUALIFICATIONS DESIRED

- Ph.D. (1-4 yrs. exper.), M.S. (5-7 yrs. exper.),   or B.S. (8+ yrs. exper.) in Organic or Medicinal  Chemistry.

- Practical experience in scientific discipline.

- Clear understanding of experimental design.

 

Description of Company

Located in Costa Mesa, Ardea Biosciences is focused on the discovery, development and commercialization of novel treatments for HIV, cancer and inflammatory diseases.

 

Application Instructions

Please send us your resume at: careers@ardeabio.com.  

Visit us at www.ardeabiosciences.com.

 

                                           

CHEMPLOYMENT 612

 

Position Title

Sr. Scientist - Process Chemistry

 

Job Description

- Design and develop synthetic routes geared to optimizing the chemical synthesis of drug  candidates. 

- Design synthetic targets and viable synthetic  routes, and synthesize target molecules  optimizing the scale-up process,

   while  maintaining efficacy

- Assess, analyze, and provide solutions to the viability of synthetic sequences as practical routes for drug candidates

- Conduct and interpret spectral and other  analytical data independently

- Conduct organic compound separation  techniques

- Demonstrate principles of working under  cGMP

- Present data and compose scientific papers for publication

 

QUALIFICATIONS DESIRED

- Ph.D. (1-4 yrs. exper.), M.S. (5-7 yrs. exper.), or B.S. (8+ yrs. exper.) in Organic or  Medicinal Chemistry

-  Practical experience in scientific discipline.

-  Clear understanding of experimental design.

 

Description of Company

Located in Costa Mesa, Ardea Biosciences is focused on the discovery, development and commercialization of novel treatments for HIV, cancer and inflammatory diseases.

 

Application Instructions

Please send us your resume at: careers@ardeabio.com.  

 

Visit us at www.ardeabiosciences.com.

 

 

CHEMPLOYMENT 614

 

Position Title

Research Associate II/III

 

Job Description

Under direct supervision, RA is expected to execute experiments, interpret results, and is individually responsible for the accuracy or scientific research, documentation of results, and the evaluation/analysis of data.

Essential duties include:

- Synthesis of compounds and intermediaries  for internal and external screening using both conventional and microwave

   assisted  chemistry

- Parallel and high throughput synthesis for  lead discovery and optimization

- Analysis of reaction products using modern spectroscopic methods

- Documentation of experiments in Electronic   Lab Journal format

 

QUALIFICATIONS DESIRED

Education

BS/MS or equivalent, with 2-5 years of experience.

 

Experience

Organic Synthesis, experience with heterocyclic chemistry preferred.  Computing and technical abilities with respect to instrumentation are essential.

 

Description of Company

Arena is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing innovative oral drugs for patients with serious diseases and disorders, such as obesity and insomnia. We have a diverse portfolio of drug candidates, both proprietary and partnered. Our lead proprietary drug candidate, lorcaserin hydrochloride, is intended for the treatment of obesity and is being evaluated in a Phase 3 clinical program.

 

Application Instructions

Email resume to jobs@arenapharm.com

 

RE: Job#01250307

 

           

CHEMPLOYMENT 615

 

Position Title

Senior Research Associate /Assistant Scientist, Medicinal Chemistry

 

Job Description

Under the direction of a Ph.D. chemist, you will design synthesize and scale-up molecules to support the company's drug discovery program efforts. In addition, the successful candidate will participate in Ligand's drug discovery process as part of a multi-disciplinary team.

 

QUALIFICATIONS DESIRED

Qualified candidates will have 1-5 years related industry experience along with a BS/MS Organic Chemistry or closely related degree. (Job title is dependent upon related industry experience and skills).

 

Description of Company

LIGAND Pharmaceuticals Inc., a San Diego-based biotech company, discovers and develops new drugs for the treatment of major unmet patient needs.

 

Ligand offers an attractive salary and comprehensive benefits package, including stock options.

 

Application Instructions

Please submit your resume via Ligand's website  at www.ligand.com

 

                                           

CHEMPLOYMENT 616

 

Position Title

Senior Scientist

 

Job Description

<>Senomyx seeks an outstanding Senior Scientist to work within our chemistry department. As part of a multidisciplinary project team, successful candidates will create new receptor-targeted small molecules  that modulate taste. Candidates will be required to evaluate relevant  biological data and use this information for the design and synthesis   
of compounds for lead optimization, as well as synthesize key building blocks and develop novel chemistry approaches as needed. Experience with multi-step organic chemistry on various scales and analytical techniques (HPLC, NMR) are required. The ideal candidate must be able to communicate effectively with other departments such as biology, sensory, and high throughput screening, as well as provide direction

and leadership within the chemistry department.

 

 

QUALIFICATIONS DESIRED

Ph.D. in organic/medicinal chemistry and 5+ years of experience. Previous experience with lead optimization or medicinal chemistry in the pharmaceutical or biotech industry is a  plus. Excellent written and verbal communication skills and the ability  to work in a fast-paced, goal-oriented team environment are  essential. The group emphasizes project leadership and encourages creativity and innovation.

 

Application Instructions

If you are interested in learning more about how you can apply to join the team, please visit our website, www.senomyx.com, for details:

 

Senomyx, Inc

ATTN: HR,

4767 Nexus Centre Dr.

San Diego, CA 92121

 

You may also submit your resume to:  human.resources@senomyx.com

 

Equal Opportunity Employer      

 

 

CHEMPLOYMENT 617

 

Position Title

Research Associate/Senior Research Associate          

 

Job Description

Senomyx seeks an outstanding research associate or senior research associate to work within our chemistry dept. As part of a  multidisciplinary project team, you will create new receptor-targeted small molecules that modulate taste. Responsibilities include designing and developing novel chemistry approaches, synthesizing intermediates

on a large scale, evaluating biological activity of hits, and optimizing lead compounds. Experience with multi-step organic chemistry  on various scales and analytical techniques (HPLC, NMR) are required. Positions at the research associate and senior research associate  levels are available.

 

QUALIFICATIONS DESIRED

Candidates should have a B.S./M.S. in organic  chemistry and 3+ years of industrial experience. Strong written and  verbal communication skills, as well as the ability to work  independently in a team-based environment, are essential.

 

Application Instructions

If you are interested in learning more about how you can apply to join  the team, please visit our website, www.senomyx.com, for details:

 

Senomyx, Inc.

ATTN: HR,

4767 Nexus Centre Dr.

 San Diego, CA 92121.

 

You may also submit your resume to: human.resources@senomyx.com

 

Equal Opportunity Employer

 

 

CHEMPLOYMENT 618

 

Position Title

Research Associate, Medicinal Chemistry

 

Job Description

<>Responsibilities will include independent planning and conducting multi-step syntheses of target molecules as potential drug candidates. Responsibilities include interpreting spectroscopic data, using the chemistry literature to solve synthetic problems, and applying modern chromato-graphic techniques to purify targets. Excellent organizational, analytical and problem solving skills are required. In this position, the candidate will have the opportunity to interact regularly with members of other departments and present findings in project meetings as

required.

 

QUALIFICATIONS DESIRED

The candidate must have a B.S. or M.S. degree in Synthetic Organic Chemistry and five (5+) years of organic synthesis experience, preferably in a medicinal chemistry laboratory. Candidate must be proficient in modern organic synthesis and purification techniques. The ability to solve problems and work independently while contributing to a project team environment is highly desired. This position requires adhering to good laboratory practices and high safety standards. Excellent written and oral communication skills and strong computer skills are essential.

 

Education

B.S. or M.S, Synthetic Organic Chemistry

 

Experience

5+ Years

 

Description of Company

SGX Pharmaceuticals is a biotechnology company focused on the discovery and development and commercialization of innovative cancer therapeutics. We have an exciting opportunity for a Research Associate, Medicinal Chemistry.

 

Application Instructions

Mail or fax  resume to:  Apply online at http://www.sgxpharma.com    

CHEMPLOYMENT 619

 

Position Title

Production Chemist IV

 

Job Description

To support our success and continued growth, Biosite is seeking a Sr Production Chemist II to join our Particle Chemistry team at our corporate headquarters in San Diego, CA.

 

This position in the Particle Chemistry  Dept. entails the production of protein conjugates and micro-particles used in the manufacture of medical diagnostic products. Responsibilities include, but are not limited to, the following:

performing complex tasks according to established procedures;  generating document revisions;  supporting process troubleshooting;

validations, statistical analysis;  improvement activities;   new product transfers.

This is a challenging opportunity ideal for a motivated individual who is seeking an opportunity to play an integral role in the growth of a dynamic and fast-paced biotech business. A successful candidate will have attention to detail, flexibility to adapt to the changing needs of the team, and eagerness to learn.

 

QUALIFICATIONS DESIRED

This position  requires  a B.S. degree in a scientific discipline and a minimum of 6-8 yrs. related experience. Knowledge of regulatory guidelines including QSR, ISO 13485, and CMDR is desired.

 

Description of Company

Biosite's research and manufacturing campus is located in the Sorrento Mesa area of San Diego between the 805 & 15 freeways. Among its amenities, Biosite offers its own cafe, fitness center, volleyball and basketball courts, soccer field, and nearby running trails, to encourage work-life balance for its employees. Biosite offers competitive salaries (commensurate with skills and experience), generous health and welfare plans.  EOE

 

Application Instructions

Please submit resume online to www.biosite.apply2jobs.com and feel free to inquire or follow up with an e-mail to:    

 

Rob Mayers

Staffing Specialist

Biosite, Inc.

rmayers@biosite.com