C
H E M P
L O Y M E N T A B S T R A C T
S - JUNE
2007
CHEMPLOYMENT 615
Position Title
Senior Research Associate /Assistant
Scientist, Medicinal
Chemistry
Job Description
Under the direction of a Ph.D. chemist,
you will design
synthesize and scale-up molecules to support the company's drug
discovery
program efforts. In addition, the successful candidate will participate
in
Ligand's drug discovery process as part of a multi-disciplinary team.
QUALIFICATIONS DESIRED
Qualified candidates will have 1-5 years
related industry
experience along with a BS/MS Organic Chemistry or closely related
degree. (Job
title is dependent upon related industry experience and skills).
Description of Company
LIGAND Pharmaceuticals Inc., a San
Diego-based biotech
company, discovers and develops new drugs for the treatment of major
unmet
patient needs.
Ligand offers an attractive salary and
comprehensive
benefits package, including stock options.
Application Instructions
Please submit your resume via Ligand's
website at www.ligand.com
CHEMPLOYMENT
616
Position
Title
Senior Scientist
Job
Description
Senomyx seeks an outstanding Senior Scientist to
work within
our chemistry department. As part of a multidisciplinary project team,
successful candidates will create new receptor-targeted small molecules that modulate taste. Candidates will be
required to evaluate relevant
biological data and use this information for the design and
synthesis
QUALIFICATIONS
DESIRED
Ph.D. in organic/medicinal chemistry and 5+ years
of
experience. Previous experience with lead optimization or medicinal
chemistry
in the pharmaceutical or biotech industry is a plus.
Excellent written and verbal communication skills and
the ability to work in a fast-paced,
goal-oriented team environment are
essential. The group emphasizes project leadership and
encourages
creativity and innovation.
Application
Instructions
If you are interested in learning more about how
you can
apply to join the team, please visit our website, www.senomyx.com, for
details:
Senomyx, Inc. - ATTN: HR,
4767 Nexus Centre Dr.,
San Diego, CA 92121
You may also submit your resume to:
human.resources@senomyx.com
Equal Opportunity Employer
CHEMPLOYMENT 617
Position Title
Research Associate/Senior Research Associate
Job Description
Senomyx seeks an outstanding research associate or
senior
research associate to work within our chemistry dept. As part of a
multidisciplinary project team, you will create new receptor-targeted
small
molecules that modulate taste. Responsibilities include designing and
developing
novel chemistry approaches, synthesizing intermediates on a large
scale,
evaluating biological activity of hits, and optimizing lead compounds.
Experience with multi-step organic chemistry on various scales and
analytical
techniques (HPLC, NMR) are required. Positions at the research
associate and
senior research associate
levels are available.
QUALIFICATIONS DESIRED
Candidates should have a B.S./M.S. in organic
chemistry and
3+ years of industrial experience. Strong written and
verbal communication skills, as well as the ability to
work independently in a team-based
environment, are essential.
Application Instructions
If you are interested in learning more about how
you can
apply to join the team, please
visit our website, www.senomyx.com, for details:
Senomyx, Inc.
ATTN: HR,
4767 Nexus Centre Dr.
San Diego, CA 92121.
You may also submit your resume to:
human.resources@senomyx.com
Equal Opportunity Employer
CHEMPLOYMENT
618
Position
Title
Research Associate, Medicinal
Chemistry
Job
Description
Responsibilities will include independent planning
and
conducting multi-step syntheses of target molecules as potential drug
candidates. Responsibilities include interpreting spectroscopic data,
using the
chemistry literature to solve synthetic problems, and applying modern
chromato-graphic techniques to purify targets. Excellent
organizational,
analytical and problem solving skills are required. In this position,
the
candidate will have the opportunity to interact regularly with members
of other
departments and present findings in project meetings as required.
QUALIFICATIONS
DESIRED
The candidate must have a B.S. or M.S. degree in
Synthetic
Organic Chemistry and five (5+) years of organic synthesis experience,
preferably in a medicinal chemistry laboratory. Candidate must be
proficient in
modern organic synthesis and purification techniques. The ability to
solve
problems and work independently while contributing to a project team
environment is highly desired. This position requires adhering to good
laboratory practices and high safety standards. Excellent written and
oral
communication skills and strong computer skills are essential.
Education
B.S. or M.S, Synthetic Organic
Chemistry
Experience
5+ Years
Description
of Company
SGX Pharmaceuticals is a biotechnology company
focused on
the discovery and development and commercialization of innovative
cancer
therapeutics. We have an exciting opportunity for a Research Associate,
Medicinal Chemistry.
Application
Instructions
Mail or fax resume
to: Apply online at
http://www.sgxpharma.com
CHEMPLOYMENT 619
Position Title
Production Chemist IV
Job Description
To support our success and continued growth,
Biosite is
seeking a Sr Production Chemist II to join our Particle Chemistry team
at our
corporate headquarters in San Diego, CA.
This position in the Particle Chemistry Dept.
entails the
production of protein conjugates and micro-particles used in the
manufacture of
medical diagnostic products. Responsibilities include, but are not
limited to, the
following:
- performing complex tasks according to
established
procedures;
- generating document revisions;
- supporting process troubleshooting;
- validations, statistical analysis;
- improvement activities;
- new product transfers.
This is a challenging opportunity ideal for a
motivated
individual who is seeking an opportunity to play an integral role in
the growth
of a dynamic and fast-paced biotech business. A successful candidate
will have
attention to detail, flexibility to adapt to the changing needs of the
team,
and eagerness to learn.
QUALIFICATIONS DESIRED
This position
requires a B.S. degree in a
scientific discipline and a minimum of 6-8 yrs. related experience.
Knowledge
of regulatory guidelines including QSR, ISO 13485, and CMDR is desired.
Description of Company
Biosite's research and manufacturing campus is
located in
the Sorrento Mesa area of San Diego between the 805 & 15 freeways.
Among
its amenities, Biosite offers its own cafŽ, fitness center, volleyball
and
basketball courts, soccer field, and nearby running trails, to
encourage
work-life balance for its employees. Biosite offers competitive
salaries
(commensurate with skills and experience), generous health and welfare
plans. EOE
Application Instructions
Please
submit resume online to www.biosite.apply2jobs.com and feel free to
inquire or
follow up with an e-mail to:
Rob
Mayers, Staffing Specialist
Biosite,
Inc.
rmayers@biosite.com
CHEMPLOYMENT 620
Position Title
Principal Scientist – In Vitro
Job Description
Will lead the in vitro screening efforts to evaluate metabolic
stability,
uptake, and efflux of early stage developmental compounds. Work to
include:
- Developing and improving
assays to evaluate metabolic stability of discovery compounds
- Coordinating and monitoring
CRO activities for absorption/transport studies
- Designing and conducting in
vitro drug metabolism studies
- Interpreting data
independently and solving problems efficiently
- Presenting data at internal
DMPK meetings or project meetings, and composing scientific papers for
publication
- Keeping current with ongoing
development of in vitro
screening
technologies and making
recommendations
for adoption of new assays
QUALIFICATIONS DESIRED
- Doctoral degree (Ph.D.) in
Chemistry or Pharmacology
- 4+ years post-doctoral or
industrial hands-on experience running metabolic stability, uptake, or
efflux
assays
- Strong communication
and instrumentation skills
- Experience using LC-MS/MS
techniques is a plus
Description of Company
Located in Costa Mesa, Ardea Biosciences is
focused on the
discovery, development and commercialization of novel treatments for
HIV,
cancer and inflammatory diseases.
Application Instructions
Please
send us your resume at: careers@ardeabio.com. Visit us at www.ardeabiosciences.com.
CHEMPLOYMENT 621
Position Title
Synthetic/Medicinal Chemist
Job Description
The successful candidate will
design and synthesize biologically interesting molecules in support of
hit
optimization, hit-to-lead, and lead optimization projects.
QUALIFICATIONS DESIRED
Education
Minimum B.S - Ph.D. in Synthetic Organic
or Medicinal
Chemistry
Experience
1-2 years of medicinal chemistry
experience in an industrial environment. Expertise in multi-step
organic
synthesis and modern methods of compound characterization is necessary.
Thorough record-keeping practices, and excellent written and verbal
communication skills are essential. Candidates familiar with
parallel/small library synthesis, is a plus.
Description of Company
For more information regarding our
company, please visit
our website at www.biofocusdpi.com
Application Instructions
Please email your application to
jobs_us@glpg.com and
reference Job Code: SD002
CHEMPLOYMENT 622
Position Title
Medicinal Chemistry Team Leader
Job Description
Duties include supervising a small team
of medicinal
chemists involved with hit-to-lead and lead optimization drug discovery
projects. Skills include drug design and optimization skills, synthetic
skills,
team and project management skills and the ability to productively
interact
with customers. The position will involve composing and presenting
detailed
reports and some travel to visit client sites. Excellent
communication
skills are required.
QUALIFICATIONS DESIRED
Experience: Experience supervising
PhD level
scientists with 5 years working in pharmaceutical setting having a
track record
of success in hit-to-lead and lead optimzation projects.
Experience with
modern methods of drug discovery including computer assisted drug
design,
parallel synthesis and expertise in analyzing biological and ADMET
data.
Description of Company
For more information regarding our
company, please visit
our website at www.biofocusdpi.com
Application Instructions
Please email your application to
jobs_us@glpg.com and
reference job code SD12
CHEMPLOYMENT 623
Position Title
Sr. Sensor Scientist
Job Description
QUALIFICATIONS DESIRED
Education
BS/MS degree in Electrochemistry, Organic
Chemistry,
engineering sciences.
Experience
Minimum 2 years relevant, combined
experience in
electrochemical sensors design, with 5 years experience with membrane
synthesis/characterization.
Description of Company
SenDx Medical, Inc., an innovator in the
medical
electronics industry develops, manufactures and markets proprietary
point-of-care blood analysis systems that provide measurement of
critical
diagnostic
parameters for the health care market.
Application Instructions
Email resume to resumes03@sendx.com or
fax to
760-930-6320.
CHEMPLOYMENT
624
Position
Title
Research
Associate III
Job
Description
Research
Associates contribute to the design of
experiments in collaboration with a supervisor. They are expected
to be
able to execute experiments and interpret results, often
independently.
RAs are individually responsible for accuracy of scientific research,
documentation of results, and the evaluation/ analysis of data.
Computing and
technical abilities with respect to instrumentation are essential.
QUALIFICATIONS
DESIRED
-
Synthesis of compounds and intermediates for internal and
external screening against GPCRs using both
conventional and microwave assisted chemistry
-
Parallel and high throughput synthesis for lead discovery
and optimization
-
Analysis of reaction products using modern spectroscopic
methods
-
Documentation of experiments in an Electronic Lab Journal
format
SPECIFIC
SKILLS:
-
Organic Synthesis, experience with heterocyclic chemistry
preferred.
Education
BS/MS
or equivalent
Experience
2-5
years experience preferred
Description
of Company
Arena
Pharmaceuticals is a clinical-stage
biopharmaceutical company focused on discovering, developing and
commercializing
innovative oral drugs for patients with serious diseases and disorders,
such
as obesity and insomnia.
Arena offers an
exciting work
environment, competitive salary, excellent benefits package, including
401(k)
and stock options.
Application
Instructions
Email
resume to: Jobs@arenapharm.com Re: Job Code: 02250407
CHEMPLOYMENT 625
Position Title
Research Scientist, Medicinal
Chemistry
Job Code: 07-009
Job Description
We are seeking
positive, highly
motivated individuals who enjoy working as part of a team.
As a Research Scientist in our
Medicinal Chemistry department, you will support a project team of
chemists
with independent research to design, synthesize, and isolate analogues
of lead
structures. In addition, the
successful candidate will participate in LigandÕs drug discovery
process as
part of a multi-disciplinary team.
QUALIFICATIONS DESIRED
A Ph.D. in Organic
Chemistry is
required along with 0-3 years research experience in industry.
Description of Company
Ligand
Pharmaceuticals Inc.
discovers and develops new drugs that address critical unmet medical
needs of
patients in the areas of thrombocytopenia, cancer, hepatitis C,
hormone-related
diseases, osteoporosis and inflammatory diseases. Ligand's proprietary
drug
discovery and development programs are based on its leadership position
in gene
transcription technology, primarily related to intracellular receptors.
Application Instructions
Ligand offers an
attractive
compensation and progressive benefits package, a professional
atmosphere, an
on-site cafe and much more! For more information about us, see
our
website at www.ligand.com.
Please
submit your
resume (including
salary expectations) for immediate consideration.
CHEMPLOYMENT 626
Position Title
Senior Research Associate /
Assistant Scientist our
Medicinal Chemistry Department
Job Code: 07-002
Job Description
As a Medicinal Chemist, under the direction of a
Ph.D.
chemist, you will design synthesize and scale-up molecules to support
the
companyÕs drug discovery program efforts. In addition, the
successful candidate
will participate in LigandÕs drug discovery process as part of a
multi-disciplinary team.
QUALIFICATIONS DESIRED
Qualified candidates will have 1-5 years related
industry
experience along with a BS/MS Organic Chemistry or closely related
degree.
Position title will be dependent upon industry
experience, education, proven knowledge and skills of the successful
candidate.
Description of Company
Ligand Pharmaceuticals Inc. discovers and develops
new drugs
that address critical unmet medical needs of patients in the areas of
thrombocytopenia, cancer, hepatitis C, hormone-related diseases,
osteoporosis
and inflammatory diseases. Ligand's proprietary drug discovery and
development
programs are based on its leadership position in gene transcription
technology,
primarily related to intracellular receptors.
Application Instructions
Ligand offers an attractive compensation and
progressive
benefits package, a professional atmosphere, an on site cafe and much
more! For more information about us, see our website at www.ligand.com.
Please submit your resume (including salary
expectations)
for immediate consideration.
CHEMPLOYMENT 627
Position Title
Senior Scientific Associate (555AL)
Job Description
This
position is responsible
for analytical laboratory work in support of pharmaceutical process
development. Responsibilities include troubleshooting existing methods,
developing new methods and performing analyses using analytical
techniques such
as HPLC and GC. This position will also be responsible for supporting
structure
elucidation activities via preparatory scale separation and mass
spectrometry.
QUALIFICATIONS DESIRED
Education/Experience
Requirements
include an M.S.
in Chemistry and 0-2 years of experience in the biotech/pharmaceutical
industry
or a B.S. with 4+ years of experience using a variety of analytical
techniques.
Familiarity with GLP/GMP regulations is a plus.
Description of Company
Vertex
Pharmaceuticals
Incorporated is a global biotechnology company committed to the
discovery and
development of break-through small molecule drugs for serious diseases.
The
CompanyÕs strategy is to commercialize its products both
independently and in
collaboration with major pharmaceutical companies. VertexÕs
product pipeline is
focused on viral diseases, inflammation, autoimmune diseases, cancer,
pain and
bacterial infection. Vertex co-discovered the HIV protease inhibitor,
Lexiva,
with GlaxoSmithKline.
Application Instructions
Please apply
directly online
through our website at: www.vrtx.com
E.O.E.
CHEMPLOYMENT 628
Position Title
Research Associate / Synthetic
Chemistry
Job Description
The successful candidate will work
in a collaboratative environment to synthesize and characterize organic
small
molecules in ongoing drug discovery projects. The individual will
execute
multi-step synthetic routes to desired target molecules on milligram
and
multigram scale. The individual will purify and separate compounds by
modern
isolation techniques and perform structure elucidation and
characterization of
compounds related to lead
optimization.
QUALIFICATIONS DESIRED
The ideal candidate will have a BS or MS
organic chemistry
and 2-5 years of laboratory experience in synthetic organic chemistry
or
medicinal. Working knowledge in modern organic chemistry and skills in
routine
methods of compound isolation and chromatographic purification
techniques are
essential. The ideal candidate
will also posses knowledge of Chem4 D, DiscoveryGate, ACD ChemDraw,
Scifinder,
MS Excel MS PowerPoint, MS Word and MS Outlook at an intermediate to
advanced
skill level.
Description of Company
Tanabe Research
Laboratories
U.S.A., Inc. (TRL), is a wholly owned subsidiary of Tanabe Seiyaku Co.,
Ltd.,
headquartered in Osaka, Japan. TRLÕs is focused on small
molecule drug
discovery in the areas of inflammation, autoimmunity & metabolic
disease.
Application Instructions
E.O.E.
CHEMPLOYMENT ABSTRACT
629
POSITION TITLE:
Sr. Research Associate/Scientist -
Analytical Chemistry
JOB DESCRIPTION:
This individual will be part of a core analytical team that supports
high-throughput medicinal chemistry
activities. Ability to: solve separation issues; perform
high-throughput analysis and/or
purification of individual compounds and compound libraries; perform
necessary
HPLC equipment maintenance and repair;
track data and prepare QC reports using Excel and Adobe.
QUALIFICATIONS DESIRED:
Education
BS/MS/Ph.D. in Analytical Chemistry or
related field.
Experience
Minimum of 2 years of experience.
Skilled in the
operation of HPLC, ESI/APCI mass spectrometers, ELSD/UV detectors, and Gilson liquid handlers.
Familiarity with Shimadzu purification systems
and Analyst/Unipoint/Gilson software is highly desirable.
Proficiency with Microsoft Excel and Adobe software required.
Strong
written and verbal communication
skills are a must.
DESCRIPTION OF COMPANY:
CRL is a chemistry-based drug discovery
company.
APPLICATION INSTRUCTIONS:
E Mail resume to:
hr@chembridgeresearch.com