C H E M P L O Y M E N T A B S T R A C T S - OCTOBER 2006

 

 

CHEMPLOYMENT 590

 

Position Title

Research Associate II
Department: Research Chemistry

(AMLN-02230)

 

Job Description

Synthesize, purify and characterize peptides and peptidomimetics.

 

Conduct physicochemical studies of peptides.

 

Be actively involved in SAR analysis and the design and synthesis of follow-up molecules.

 

Assist in maintaining laboratory instruments and inventory of chemicals and reagents.

 

Keep abreast of current literature in relevant programs.

 

Education

BS/MS degree in Organic Chemistry or closely related scientific field.

 

Experience

3-5 years of research experience in peptide or medicinal chemistry.

 

Demonstrable expertise in modern analytical and separation techniques (TLC, HPLC, NMR, LC-MS, etc.).

 

Experience with automated peptide synthesis a plus.

 

Proven ability to conduct self-directed research and development would be advantageous.

 

Description of Company

Amylin Pharmaceuticals is committed to improving the lives of people with diabetes and other metabolic diseases through the discovery, development, and commercialization of innovative, cost-effective medicines.

 

Location: San Diego, CA

 

Application Instructions

Please apply online at: http://careers.amylin.com

AA/EEO Employer.          

 

 

CHEMPLOYMENT 591

 

Position Title

Development Scientist

 

QUALIFICATIONS DESIRED

As a Development Scientist on our Analytical Development team, you will assist in the efforts of commercial and development stability programs for drug substances and drug products. Requirements include: BS in Chemistry or closely related degree, 5+ years experience in the pharmaceutical industry, analytical chemistry and chromatography expertise, working knowledge of GLP/GMP regulations, excellent communication skills and the ability to work within a team setting.

 

Description of Company

Ligand Pharmaceuticals Inc. is an emerging specialty pharmaceutical company located in the Torrey Pines area of San Diego..

 

Application Instructions

LIGAND offers an attractive compensation and progressive benefits package. To submit your resume, please visit our website at www.ligand.com

(Job Code 06-075).

 

EOE

 

                                           

CHEMPLOYMENT 592

 

Position Title

Ink Chemist Ð Requisition # 966999

 

Job Description

This position will be located in San Diego, CA.

Development of colorants and ink formulations that provide industry-leading advantages for HP's inkjet products. Interaction with external suppliers in pursuit of colorants or other technology for use by HP. Communication of your work at appropriate forums include. staff meetings and reviews. Travel, as needed, to partner media and printer divisions, external suppliers, and conferences/ trade-shows. Take an active role in patent generation. Research and identify causes of formulation, design or technical problems. Analysis and evaluation of new materials and formulations to ensure meeting of regulatory and HP quality standards.

 

Qualifications Desired: Master's degree in chemistry, polymer science, chemical engineering, material science. Ph.D. degree highly desired. Demonstrated under-standing of inkjet printers and writing systems. Analytical problem-solving and decision making skills. Screening and design-of-experiments experience. Excellent team-work, communication and documentation skills. Able to work effectively with external partners at a technical and interpersonal level and to make clear and effective presentations to inform and persuade peers and managers. Prior experience working with external suppliers, vendors or manufacturers.

 

Description of Company

HP is the world leader in ink jet printing. We invent new technologies and innovative information products. Change markets. Create business opportunities. We also help to plan and broaden company strategy, and deliver the science and technology that achieves it. And that gives HP leadership. We're focused on e-servicesÉtechnologies and solutions. On internet and computing platforms, printing and imaging technologies, storage and intelligent information appliances, and we're chasing down broader alternative technologies and basic research.

 

Application Instructions

Please apply on-line at www.hp.com/go/jobs and use the keyword 966999      

 

 

CHEMPLOYMENT 593

 

Position Title:

Senior Process Chemist

 

Job Description:

Independent design of efficient synthetic routes for scale-up.

 

Independent development and optimization of scaleable cost-effective processes for small molecule new drug candidates based on a sound mechanistic understanding of reactions and processes.

 

Working with analytical chemists to develop appropriate analytical methods for in-process assays and final product characterization and analyses.

 

Perform scale-up activities to prepare multigram to kilogram quantities of new drug candidates in the laboratory and in 10- to 50-L reactors to support clinical candidate selection and pre-clinical development.

 

Design and synthesis of new drug candidate impurity and metabolite standards to support pre-clinical and clinical development.

 

Technical transfer of scaleable processes to collaborating partners or custom manufacturing organizations, including assistance in trouble-shooting if necessary.

 

Documentation and reporting of results such as process descriptions, batch records, development reports, presentations, patent applications, and publications.

 

Education

Ph.D. in Organic Chemistry

 

Experience:

5 years industrial experience

 

Description of Company:

Anadys Pharmaceuticals, Inc. is a biopharmaceutical company committed to advancing patient care by discovering, developing and commercializing novel small molecule medicines for the treatment of hepatitis, other serious infections, and cancer.

 

Application Instructions:

Please apply through our website http://www.anadyspharma.com.

 

 

CHEMPLOYMENT 594

 

Position Title

Synthetic/Medicinal Chemist

 

Job Description

The successful candidate will design and synthesize of biologically interesting molecules in support of hit to lead and lead optimization projects.

 

Key requirements include a Ph.D. in synthetic organic or medicinal chemistry plus 2 to 8 years of additional synthetic or medicinalchemistry experience. Expertise in multistep organic synthesis is essential; including modern methods of compound characterization, thorough record-keeping practices, and excellent written and verbal communication skills is essential.

 

Medicinal chemistry experience in an industrial environment, ideally including parallel/small library synthesis, is a plus.

 

Description of Company

We invite you to visit our website at www.biofocusdpi.com to learn more about our company.

 

Application Instructions

If you have the right qualifications for this job please send your CV and reference job code (SD 002) to:

 

HR Department

Email: jobs_us@glpg.com          

 

 

CHEMPLOYMENT 595

 

Position Title

Research Scientist (Contract)

 

Job Description:

We seek a synthetic chemist to support our top priority drug discovery projects. Primary responsibilities will include:

 

Independent synthesis, purification and characterization of both parallel synthesis libraries of compounds as well as multi-step serial synthesis compound projects.

 

Detailed routine documentation and periodic formal presentation of all work.

 

Regular performance of literature and compound database searches to support projects

 

Education:

Bachelor's degree in Synthetic Chemistry with 8+ yrs. experience or Master's degree with 5+ yrs. relevant industrial experience or PhD with 2-5 yrs. relevant industrial or academic research experience in synthetic chemistry

 

Experience:

Proven ability to independently set up, execute and monitor a variety of synthetic reactions in both a serial and parallel format.

 

Experience in all types of purification and characterization techniques.

 

Excellent understanding of all aspects of modern multi-step synthetic chemistry methods and analytical techniques.

 

Experience with automated LC/MS or preparative HPLC instrumentation is highly desirable.

 

Description of Company

Vertex Pharmaceuticals Inc. is leading the way in small molecule drug discovery. By pioneering new, innovative, faster approaches to drug discovery with a focus on chemo-genomics, our goal is to set the standard for pharmaceutical research and development in the 21st Century. Our HIV protease inhibitor, Agenerase, is currently marketed in partnership with GlaxoSmithKline, and we have a broad array of promising drug candidates expected to launch in the coming years. It's a pipeline packed with huge potential, and it's only at Vertex.

 

Application Instructions

Email your resume and cover letter to hr@sd.vrtx.com and reference Research Scientist (Contract)

 

Fax to 858-404-6720

 

Vertex Pharmaceuticals Inc. is an EQUAL OPPORTUNITY EMPLOYER.

 

 

CHEMPLOYMENT 596

 

Position Title

Product Representative

 

Job Description

Making product demonstrations and presentations to clients in the pharmaceutical and biotechnolgy industries about the H-Cube desk top hydrogenator. Product installations and service.

The position is based in Budapest, Hungary.

 

QUALIFICATIONS DESIRED

Education

MSc or PhD Chemist with outgoing personality, fluent in English.

 

Experience

Industrial experience is preferred.

 

Description of Company

Thales Nano specializes in the design and manufacture of microfluidic based chemical reactors. Thales Nano creates instruments that meet the needs of chemists and move the boundaries of chemical synthesis in new directions. Its H-Cube hydrogenator has been enthusiastically received and is used by 9 of the top 10 pharmaceutical companies in the world. The H-Cube received the R&D 100 Award in 2005.

 

 

Application Instructions

For more information contact:

 

Alex Drijver

CEO

Thales Nanotechnology

alex.drijver@thalesnano.com

www.thalesnano.com