C
H E M P
L O Y M E N T A B S T R A C T
S - March
2007
CHEMPLOYMENT 603
Position Title
Research Associate II –
Medicinal Chemistry
Job Description
The Research Associate
II, Medicinal Chemistry, will
support the efforts of the Medicinal Chemistry group as part of a
multi-disciplinary project team. He
or she will
synthesize therapeutic agents for the treatment of metabolic and
infectious
disorders and other therapeutic areas.
QUALIFICATIONS
DESIRED
Education
Bachelors Degree in
modern synthetic chemistry plus at
least 2 years of relevant industry experience, or Masters Degree in
modern
synthetic chemistry.
Experience
Prior experience in
designing and conducting multi-step
syntheses of therapeutic molecules desired.
Description of
Company
Phenomix
Corporation invents and develops novel drugs to inhibit therapeutic
targets in
the protease and kinase families. Phenomix has a portfolio of programs
underway
in multiple indications. The most advanced programs are a Phase 2
inhibitor of
the protease DPP4 for treatment of Type 2 diabetes and a preclinical
program
inhibiting NS3 protease for treatment of hepatitis C.
Further information on our programs may be found on our
website at www.phenomix.com.
Application
Instructions
Please forward your
resume to jobs@phenomix.com.
CHEMPLOYMENT 604
Position Title
Student Intern
Job Description
Synthesize
compounds for medical chemistry drug discovery projects.
QUALIFICATIONS
DESIRED
College
organic chemistry course, and lab course.
Description of
Company
Metabasis
Therapeutics, Inc. is a San Diego-based biopharmaceutical company
focused on
the discovery, development and commercialization of novel therapies to
address
some of the world's most widespread and costly chronic diseases.
Metabasis has
a broad product pipeline targeting large markets with significant unmet
medical
needs. We are specifically focused on metabolic diseases involving
pathways to
the liver, such as diabetes and hyper-lipidemia, as well as liver
diseases
such as
hepatitis and liver cancer.
Application
Instructions
Email to:
jobs@mbasis.com
CHEMPLOYMENT 605
The
Research Chemistry Department at Amylin Pharmaceuticals is currently in
a high
growth phase and has 6 new positions at the following levels. Please
copy and
paste the individual link into your web browser to read the full job
description and directly apply on line.
Position Titles
Sr.
Scientific Investigator (AMLN-02765)
http://careers.amylin.com/jobDetail.asp?id=12415&p=1
Sr.
Staff Scientist (AMLN-02766)
http://careers.amylin.com/jobDetail.asp?id=12416&p=1
Staff
Scientist (AMLN-02767)
http://careers.amylin.com/jobDetail.asp?id=12417&p=1
Research
Associate II/Sr. Research Associate
(AMLN-02768) (3 Openings)
http://careers.amylin.com/jobDetail.asp?id=12418&p=1
Description of
Company
Amylin
Pharmaceuticals is committed to improving lives through the discovery,
development and commercialization of innovative medicines.
Amylin
offers competitive compensation, benefits and stock options. Amylin maintains a drug- and
alcohol-free workplace and all offers of
employment are contingent upon satisfactory completion of a pre-employment drug and alcohol test.
Application
Instructions
Please
apply online at
careers.amylin.com,
and select "Research Chemistry" as the department.
AA/EEO Employer.
CHEMPLOYMENT 606
Position Title
Scientist,
Medicinal Chemistry
Job Description
The
successful candidate will be responsible for lead optimization in the
identification of new therapeutic agents.
Key
Responsibilities
- Plan
and execute the synthesis of organic molecules for evaluation
in drug discovery
projects.
- Conduct
research towards solving problems in the synthesis of target
organic molecules.
- Evaluate
the SAR from multiple biological experiments and propose
new compounds
for chemical synthesis.
- Participate
on drug discovery project teams.
- Prepare
and communicate in both oral and written form, reports of
research results.
- Will
analyze reports from experiments and propose solutions to
problems.
QUALIFICATIONS
DESIRED
- Requires
successful track record in small molecule drug discovery, and strong
background
in modern synthetic chemistry, chromatographic, and analytical
techniques
including HPLC, NMR and MS.
Description of
Company
Phenomix Corporation
invents and develops novel drugs to
inhibit therapeutic targets in the protease and kinase families.
Phenomix has a
portfolio of programs underway in multiple indications. The most
advanced
programs are a Phase 2 inhibitor of the protease DPP4 for treatment of
Type 2
diabetes and a preclinical program inhibiting NS3 protease for
treatment of
hepatitis C. Further information
on our programs may be found on our website at www.phenomix.com.
Application
Instructions
Please
forward your resume to jobs@phenomix.com.
CHEMPLOYMENT 607
Position Title
Process Chemist/CMC
Manager
Job Description
The
Process Chemist/CMC Manager/Senior Manager, will provide
leadership in process chemistry for PhenomixÕ preclinical and
phase 1-3
development projects.
Key
Responsibilities
- Develop
strategy for process development and API manufacturing for preclinical, nonclinical and
clinical
studies and productregistration.
- Design
and
troubleshoot synthetic routes and scale up plans for API manufacturing.
- Ensure
the
API demands of companyÕs projects are met.
- Evaluate,
select, and manage process CROs.
- Write
process reports and regulatory documents.
- Source
raw
materials
QUALIFICATIONS
DESIRED
- BS/MS
with 8-10 years/Ph.D. with 3-5
years experience in process chemistry in
pharmaceutical or biotech
industry;
- Hands
on experience and track record in
pharmaceutical process development,
particularly with late
development projects;
- Familiarity
with CMC activities and
regulatory requirements;
- Proven
project management skills;
- Excellent
oral and written
communication skills.
Description of
Company
Phenomix
Corporation
invents and develops novel drugs to inhibit therapeutic targets in the
protease
and kinase families. Phenomix has a portfolio of programs underway in
multiple
indications. The most advanced programs are a Phase 2 inhibitor of the
protease
DPP4 for treatment of Type 2 diabetes and a preclinical program
inhibiting NS3
protease for treatment of hepatitis C.
Further information on our programs may be found on our website
at
www.phenomix.com.
Application
Instructions
Please forward your
resume to
CHEMPLOYMENT 608
Position Title
ADME Chemistry Position
Job Description
Positions
Role:
* Recuitment
and leadership of ADME
Scientists
* Ability
to work with a Medicinal
Chemistry group on joint lead
optimization projects
* Provide
consultancy on ADME
optimization issues
* Work
with BD to generate business
* Work
with ADME group in UK to ensure
alignment of science and business
Requirements:
* Expertise
in pharmacokinetic anaylsis
and interpretation
* Min
5+ years experience in early ADME
and development of running in vitro ADME assays
* Experience
interacting with and
supporting drug discovery projects
* Good
interpersonal, communication and
management skills
* Comfortable
giving scientific presentations
* Ability
to travel
QUALIFICATIONS
DESIRED
* 10+
years ADME industry experience
* Experience
with in silico ADME methods
and with physiochemical measurements for evaluating
potential drugs
Description of
Company
For
further information on job and company please visit our website at
www.biofocusdpi.com
Application
Instructions
email
resume to: jobs_us@glpg.com
POSITION AVAILABLE
Position Title
Research
Scientist, Medicinal Chemistry, San Diego, CA
Job Description
Medicinal chemistry.
Carry out the
design and synthesis of new chemical entities suitable for driving a
drug
discovery program from the drawing board to the clinic.
Qualifications
A Ph.D. (0-5 years) or M.S. (3-10 years) in synthetic organic chemistry with demonstrated success in modern approaches to multi-step organic synthesis is required. The successful candidates must thrive in a team oriented environment and be able to work efficiently in an early stage discovery company. Structure based drug design experience is a plus.
Description of the
Company
Trius Therapeutics is discovering and developing innovative antibacterial drugs for the treatment of life-threatening infections. The company's lead product candidate, TR-701 is a novel oral and IV oxazolidinone antibiotic with potent activity against Gram positive bacterial pathogens. Trius' pipeline includes three additional structure-based drug design programs directed against novel antibacterial targets. For more information, visit www.triusrx.com.
Application
Instructions
Interested candidates please e-mail resumes to careers@triusrx.com.
______________________________________________________________________________________________________________________
East County, San Diego, CA
CHEMISTRY INSTRUCTOR
Full Time Contract,
Tenure Track
(10 Months)
Initial Salary
Placement Range:
$41,517 - $71,685/Yr.
Starting Date: 08/13/07
Deadline:
03/16/07
Please visit our
website for full
details:
GROSSMONT-CUYAMACA
COMMUNITY
COLLEGE DISTRICT
District Employment
Services
8800 Grossmont
College Drive
El Cajon, CA
92020-1799
An Equal
Opportunity/Title IX
Employer